
고효율 크로마토그래피 분리기술 및 그 응용
크로마토그래피 분리 는 고정상과 이동상에 있는 다양한 물질의 분배 계수가 다른 것을 기반으로 하는 복합 혼합물의 성분을 분리하는 효과적인 방법입니다. 두 상이 상대 운동으로 움직일 때, 이러한 물질은 이동상과 함께 움직이며 두 상 사이에 반복적으로 분배됩니다. 따라서 다양한 물질이 다른 장소에서 용출되고 분리가 달성됩니다.
그러나 전통적인 산업용 조제 크로마토그래피는 단일 컬럼 간헐적 공급 용출의 저효율 모드에서 작동합니다. 이는 장비, 공간, 운영 및 처리 비용을 증가시켜 크로마토그래피 분리 기술의 산업화를 심각하게 제한합니다.
In chromatographic separation, because different substances have different forces on the stationary phase, one component will flow out quickly and the other component will flow out slowly during the elution process. Thus the separation of the two components will be achieved. If, during the elution process, a movement opposite to the elution direction of the mobile phase is added, the components will run like the tortoise and rabbit on the conveyor belt shown below. Under the reverse motion of conveyor belt, the distance between tortoise and rabbit will be farther and farther, and finally they will fall from different end of the conveyor belt and be separated. If the tortoises and hares are continuously added at a certain location of conveyor belt, the continuous separation of them can be achieved. Then, the
Simulated Moving Bed
(SMB) chromatographic separation
technology
comes into being.
Based on the different forces between different substances on stationary phase, SMB chromatographic separation technology combined with special technological process equipment achieves precise switching of different process pipelines through self-control technology and creates the effect of mobile chromatographic column. SMB chromatographic separation technology realizes high-efficiency and continuous chromatographic separation.
With the advanced technology and experience in the development of high-performance resins and the design of continuous ion exchange system, Sunresin had successfully developed a series of polymer chromatographic separation fillers and a universal Sepsolut
® simulated mobile bed chromatographic separation system based on the principle of simulated mobile bed chromatographic separation and the reference from to characteristics of different separation products. Sunresin succeeds in industrialization of
separation of sugar and alcohol
,
purification of amino acids
,
desaltation and decoloration of fermentation broth
,
separation of effective monomers
from plants, etc. Sunresin's products have good separation effect and are highly praised by consumers.
Sunresin's advantages in high-performance chromatographic separation system technology:
1. Development and production capacity of a full range of chromatographic packing technologies; high-level chromatographic separation technology.
2. Innovative technology; customized equipment; perfect combination of meaterial, applied technology and equipment.
Sunresin's advantages in polymer chromatographic separation filler:
1. High adsorption capacity.
2. Applicable to a wide range of pH; sodium hydroxide resistance.
3. Longer service life.
The advantages of Sepsolut
® Simulated Mobile Bed Chromatographic Separation System:
1. High separation accuracy; high-quality purified products.
2. High yield; low solvent consumption.
3. Stable system; automatic and continuous operation; convenient.
4. 높은 효율성